scleroderma?

jlcrit on Wed, 28th Jul 2010 5:31 pm 



yeah i have…my best friend’s mom died of it last Thanksgiving. here is what you should know:
Scleroderma is an autoimmune disease of the connective tissue. Autoimmune diseases are illnesses which occur when the body’s tissues are attacked by its own immune system. Scleroderma is characterized by the formation of scar tissue (fibrosis) in the skin and organs of the body. This leads to thickness and firmness of involved areas. Scleroderma is also referred to as systemic sclerosis.

The cause of scleroderma is not known. Researchers have found some evidence that genes are important factors, but the environment seems to also play a role. The result is activation of the immune system causing injury to tissues that result in injury similar to scar tissue formation. The fact that genes seem to cause a predisposition to developing scleroderma means that inheritance at least play a partial role. It is not unusual to find other autoimmune diseases in families of scleroderma patients. Some evidence for the role genes may play in leading to the development of scleroderma comes from the study of Choctaw Native Americans who are the group with the highest reported prevalence of the disease. The disease is more frequent in females than in males

hope that helps….its a horrible horrible disease

animal luver and helper!! on Wed, 28th Jul 2010 5:31 pm 



yes in fact Bob Saget has a special non profit as his sister had this dreadful disease. what do you want to know about it.

jmada05 on Wed, 28th Jul 2010 5:31 pm 



Yes,its a debilatating condition, causes stone like appearance of face,organs have trouble functioning etc. Look up on the internet re: condition. No cure has yet been found,just treat symptoms as they occur.

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